2010 NCAA Football Big East Conference Schedule
| | Cincinnati Bearcats | | Sep 4 - L at Fresno State, 14-28 | | Sep 11 - W vs. Indiana State, 40-7 | | Sep 16 - L at NC State, 19-30 | | Sep 25 - L vs. Oklahoma, 29-31 | | Oct 2 - Open | | Oct 9 - W vs. Miami-Ohio, 45-3 | | Oct 15 - W at Louisville, 35-27 | | Oct 22 - L vs. So Florida, 30-38 | | Oct 30 - L vs. Syracuse, 7-31 | | Nov 6 - Open | | Nov 13 - L at West Virginia, 10-37 | | Nov 20 - W vs. Rutgers, 69-38 | | Nov 27 - L at Connecticut, 17-38 | | Dec 4 - L vs. Pittsburgh, 10-28 |
| | Connecticut Huskies | | Sep 4 - L at Michigan, 10-30 | | Sep 11 - W vs. Texas Southern, 62-3 | | Sep 18 - L at Temple, 16-30 | | Sep 25 - W vs. Buffalo, 45-21 | | Oct 2 - W vs. Vanderbilt, 40-21 | | Oct 8 - L at Rutgers, 24-27 | | Oct 16 - Open | | Oct 23 - L at Louisville, 0-26 | | Oct 29 - W vs. West Virginia, 16-13 OT | | Nov 6 - Open | | Nov 11 - W vs. Pittsburgh, 30-28 | | Nov 20 - W at Syracuse, 23-6 | | Nov 27 - W vs. Cincinnati, 38-17 | | Dec 4 - W at So Florida, 19-16 | | Dec 11 - Open | | Jan 1 - L at Oklahoma, 20-48 |
| | Houston Cougars | | Sep 4 - W vs. Texas State, 68-28 | | Sep 10 - W vs. Texas-El Paso, 54-24 | | Sep 18 - L at UCLA, 13-31 | | Sep 25 - W vs. Tulane, 42-23 | | Oct 2 - Open | | Oct 9 - L vs. Miss State, 24-47 | | Oct 16 - L at Rice, 31-34 | | Oct 23 - W at SMU, 45-20 | | Oct 30 - W at Memphis, 56-17 | | Nov 5 - L vs. UCF, 33-40 | | Nov 13 - L vs. Tulsa, 25-28 | | Nov 20 - L at Southern Miss, 41-59 | | Nov 27 - L at Texas Tech, 20-35 |
| | Louisville Cardinals | | Sep 4 - L vs. Kentucky, 16-23 | | Sep 11 - W vs. Eastern Ky, 23-13 | | Sep 18 - L at Oregon State, 28-35 | | Sep 25 - Open | | Oct 2 - W at Arkansas State, 34-24 | | Oct 9 - W vs. Memphis, 56-0 | | Oct 15 - L vs. Cincinnati, 27-35 | | Oct 23 - W vs. Connecticut, 26-0 | | Oct 30 - L at Pittsburgh, 3-20 | | Nov 6 - W at Syracuse, 28-20 | | Nov 13 - L vs. So Florida, 21-24 OT | | Nov 20 - L vs. West Virginia, 10-17 | | Nov 26 - W at Rutgers, 40-13 | | Dec 4 - Open | | Dec 11 - Open | | Dec 21 - W vs. Southern Miss, 31-28 |
| | Memphis Tigers | | Sep 4 - L at Miss State, 7-49 | | Sep 11 - L at East Carolina, 27-49 | | Sep 18 - W vs. Middle Tennessee, 24-17 | | Sep 25 - L at Texas-El Paso, 13-16 | | Oct 2 - L vs. Tulsa, 7-48 | | Oct 9 - L at Louisville, 0-56 | | Oct 16 - L vs. Southern Miss, 19-41 | | Oct 23 - Open | | Oct 30 - L vs. Houston, 17-56 | | Nov 6 - L vs. Tennessee, 14-50 | | Nov 13 - L at Marshall, 13-28 | | Nov 20 - L at UAB, 15-31 | | Nov 27 - L vs. UCF, 17-37 |
| | Rutgers Scarlet Knights | | Sep 2 - W vs. Norfolk State, 31-0 | | Sep 11 - W at FIU, 19-14 | | Sep 18 - Open | | Sep 25 - L vs. North Carolina, 13-17 | | Oct 2 - L vs. Tulane, 14-17 | | Oct 8 - W vs. Connecticut, 27-24 | | Oct 16 - W vs. Army, 23-20 OT | | Oct 23 - L at Pittsburgh, 21-41 | | Oct 30 - Open | | Nov 3 - L at So Florida, 27-28 | | Nov 13 - L vs. Syracuse, 10-13 | | Nov 20 - L at Cincinnati, 38-69 | | Nov 26 - L vs. Louisville, 13-40 | | Dec 4 - L at West Virginia, 14-35 |
| | SMU Mustangs | | Sep 5 - L at Texas Tech, 27-35 | | Sep 11 - W vs. UAB, 28-7 | | Sep 18 - W vs. Washington St, 35-21 | | Sep 24 - L vs. TCU, 24-41 | | Oct 2 - W at Rice, 42-31 | | Oct 9 - W vs. Tulsa, 21-18 | | Oct 16 - L at Navy, 21-28 | | Oct 23 - L vs. Houston, 20-45 | | Oct 30 - W at Tulane, 31-17 | | Nov 6 - L at Texas-El Paso, 14-28 | | Nov 13 - Open | | Nov 20 - W vs. Marshall, 31-17 | | Nov 26 - W at East Carolina, 45-38 OT | | Dec 4 - L at UCF, 7-17 | | Dec 11 - Open | | Dec 30 - L vs. Army, 14-16 |
| | South Florida Bulls | | Sep 4 - W vs. Stony Brook, 59-14 | | Sep 11 - L at Florida, 14-38 | | Sep 18 - Open | | Sep 25 - W vs. Western Ky, 24-12 | | Oct 2 - W vs. Fla Atlantic, 31-3 | | Oct 9 - L vs. Syracuse, 9-13 | | Oct 14 - L at West Virginia, 6-20 | | Oct 22 - W at Cincinnati, 38-30 | | Oct 30 - Open | | Nov 3 - W vs. Rutgers, 28-27 | | Nov 13 - W at Louisville, 24-21 OT | | Nov 20 - L vs. Pittsburgh, 10-17 | | Nov 27 - W at Miami-Florida, 23-20 OT | | Dec 4 - L vs. Connecticut, 16-19 | | Dec 11 - Open | | Dec 31 - W at Clemson, 31-26 |
| | Temple Owls | | Sep 3 - W vs. Villanova, 31-24 | | Sep 9 - W vs. Central Mich, 13-10 OT | | Sep 18 - W vs. Connecticut, 30-16 | | Sep 25 - L at Penn State, 13-22 | | Oct 2 - W at Army, 42-35 | | Oct 9 - L at Northern Ill, 17-31 | | Oct 16 - W vs. Bowling Green, 28-27 | | Oct 23 - W at Buffalo, 42-0 | | Oct 30 - W vs. Akron, 30-0 | | Nov 6 - W at Kent State, 28-10 | | Nov 13 - Open | | Nov 16 - L vs. Ohio U, 23-31 | | Nov 23 - L at Miami-Ohio, 3-23 |
| | UCF Knights | | Sep 4 - W vs. South Dakota, 38-7 | | Sep 11 - L vs. NC State, 21-28 | | Sep 18 - W at Buffalo, 24-10 | | Sep 25 - L at Kansas State, 13-17 | | Oct 2 - Open | | Oct 6 - W vs. UAB, 42-7 | | Oct 13 - W at Marshall, 35-14 | | Oct 23 - W vs. Rice, 41-14 | | Oct 30 - W vs. East Carolina, 49-35 | | Nov 5 - W at Houston, 40-33 | | Nov 13 - L vs. Southern Miss, 21-31 | | Nov 20 - W at Tulane, 61-14 | | Nov 27 - W at Memphis, 37-17 | | Dec 4 - W vs. SMU, 17-7 | | Dec 11 - Open | | Dec 31 - W vs. Georgia, 10-6 |
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