2010 NCAA Football Big Ten Conference Schedule
| | Illinois Fighting Illini | | Sep 4 - L at Missouri, 13-23 | | Sep 11 - W vs. Southern Ill, 35-3 | | Sep 18 - W vs. Northern Ill, 28-22 | | Sep 25 - Open | | Oct 2 - L vs. Ohio State, 13-24 | | Oct 9 - W at Penn State, 33-13 | | Oct 16 - L at Michigan State, 6-26 | | Oct 23 - W vs. Indiana, 43-13 | | Oct 30 - W vs. Purdue, 44-10 | | Nov 6 - L at Michigan, 65-67 3OT | | Nov 13 - L vs. Minnesota, 34-38 | | Nov 20 - W at Northwestern, 48-27 | | Nov 27 - Open | | Dec 3 - L at Fresno State, 23-25 | | Dec 11 - Open | | Dec 29 - W at Baylor, 38-14 |
| | Indiana Hoosiers | | Sep 2 - W vs. Towson, 51-17 | | Sep 11 - Open | | Sep 18 - W at Western Ky, 38-21 | | Sep 25 - W vs. Akron, 35-20 | | Oct 2 - L vs. Michigan, 35-42 | | Oct 9 - L at Ohio State, 10-38 | | Oct 16 - W vs. Arkansas State, 36-34 | | Oct 23 - L at Illinois, 13-43 | | Oct 30 - L vs. Northwestern, 17-20 | | Nov 6 - L vs. Iowa, 13-18 | | Nov 13 - L at Wisconsin, 20-83 | | Nov 20 - L vs. Penn State, 24-41 | | Nov 27 - W at Purdue, 34-31 OT |
| | Iowa Hawkeyes | | Sep 4 - W vs. Eastern Ill, 37-7 | | Sep 11 - W vs. Iowa State, 35-7 | | Sep 18 - L at Arizona, 27-34 | | Sep 25 - W vs. Ball State, 45-0 | | Oct 2 - W vs. Penn State, 24-3 | | Oct 9 - Open | | Oct 16 - W at Michigan, 38-28 | | Oct 23 - L vs. Wisconsin, 30-31 | | Oct 30 - W vs. Michigan State, 37-6 | | Nov 6 - W at Indiana, 18-13 | | Nov 13 - L at Northwestern, 17-21 | | Nov 20 - L vs. Ohio State, 17-20 | | Nov 27 - L at Minnesota, 24-27 | | Dec 4 - Open | | Dec 11 - Open | | Dec 28 - W vs. Missouri, 27-24 |
| | Michigan Wolverines | | Sep 4 - W vs. Connecticut, 30-10 | | Sep 11 - W at Notre Dame, 28-24 | | Sep 18 - W vs. Massachusetts, 42-37 | | Sep 25 - W vs. Bowling Green, 65-21 | | Oct 2 - W at Indiana, 42-35 | | Oct 9 - L vs. Michigan State, 17-34 | | Oct 16 - L vs. Iowa, 28-38 | | Oct 23 - Open | | Oct 30 - L at Penn State, 31-41 | | Nov 6 - W vs. Illinois, 67-65 3OT | | Nov 13 - W at Purdue, 27-16 | | Nov 20 - L vs. Wisconsin, 28-48 | | Nov 27 - L at Ohio State, 7-37 | | Dec 4 - Open | | Dec 11 - Open | | Jan 1 - L vs. Miss State, 14-52 |
| | Michigan State Spartans | | Sep 4 - W vs. Western Mich, 38-14 | | Sep 11 - W at Fla Atlantic, 30-17 | | Sep 18 - W vs. Notre Dame, 34-31 OT | | Sep 25 - W vs. Northern Colorado, 45-7 | | Oct 2 - W vs. Wisconsin, 34-24 | | Oct 9 - W at Michigan, 34-17 | | Oct 16 - W vs. Illinois, 26-6 | | Oct 23 - W at Northwestern, 35-27 | | Oct 30 - L at Iowa, 6-37 | | Nov 6 - W vs. Minnesota, 31-8 | | Nov 13 - Open | | Nov 20 - W vs. Purdue, 35-31 | | Nov 27 - W at Penn State, 28-22 | | Dec 4 - Open | | Dec 11 - Open | | Jan 1 - L vs. Alabama, 7-49 |
| | Minnesota Golden Gophers | | Sep 2 - W at Middle Tennessee, 24-17 | | Sep 11 - L vs. South Dakota, 38-41 | | Sep 18 - L vs. USC, 21-32 | | Sep 25 - L vs. Northern Ill, 23-34 | | Oct 2 - L vs. Northwestern, 28-29 | | Oct 9 - L at Wisconsin, 23-41 | | Oct 16 - L at Purdue, 17-28 | | Oct 23 - L vs. Penn State, 21-33 | | Oct 30 - L vs. Ohio State, 10-52 | | Nov 6 - L at Michigan State, 8-31 | | Nov 13 - W at Illinois, 38-34 | | Nov 20 - Open | | Nov 27 - W vs. Iowa, 27-24 |
| | Nebraska Cornhuskers | | Sep 4 - W vs. Western Ky, 49-10 | | Sep 11 - W vs. Idaho, 38-17 | | Sep 18 - W at Washington, 56-21 | | Sep 25 - W vs. South Dakota St, 17-3 | | Oct 2 - Open | | Oct 7 - W at Kansas State, 48-13 | | Oct 16 - L vs. Texas, 13-20 | | Oct 23 - W at Oklahoma State, 51-41 | | Oct 30 - W vs. Missouri, 31-17 | | Nov 6 - W at Iowa State, 31-30 OT | | Nov 13 - W vs. Kansas, 20-3 | | Nov 20 - L at Texas A&M, 6-9 | | Nov 26 - W vs. Colorado, 45-17 | | Dec 4 - L at Oklahoma, 20-23 | | Dec 11 - Open | | Dec 30 - L at Washington, 7-19 |
| | Northwestern Wildcats | | Sep 4 - W at Vanderbilt, 23-21 | | Sep 11 - W vs. Illinois State, 37-3 | | Sep 18 - W at Rice, 30-13 | | Sep 25 - W vs. Central Mich, 30-25 | | Oct 2 - W at Minnesota, 29-28 | | Oct 9 - L vs. Purdue, 17-20 | | Oct 16 - Open | | Oct 23 - L vs. Michigan State, 27-35 | | Oct 30 - W at Indiana, 20-17 | | Nov 6 - L at Penn State, 21-35 | | Nov 13 - W vs. Iowa, 21-17 | | Nov 20 - L vs. Illinois, 27-48 | | Nov 27 - L at Wisconsin, 23-70 | | Dec 4 - Open | | Dec 11 - Open | | Jan 1 - L at Texas Tech, 38-45 |
| | Ohio State Buckeyes | | Sep 2 - W vs. Marshall, 45-7 | | Sep 11 - W vs. Miami-Florida, 36-24 | | Sep 18 - W vs. Ohio U, 43-7 | | Sep 25 - W vs. Eastern Mich, 73-20 | | Oct 2 - W at Illinois, 24-13 | | Oct 9 - W vs. Indiana, 38-10 | | Oct 16 - L at Wisconsin, 18-31 | | Oct 23 - W vs. Purdue, 49-0 | | Oct 30 - W at Minnesota, 52-10 | | Nov 6 - Open | | Nov 13 - W vs. Penn State, 38-14 | | Nov 20 - W at Iowa, 20-17 | | Nov 27 - W vs. Michigan, 37-7 | | Dec 4 - Open | | Dec 11 - Open | | Jan 4 - W at Arkansas, 31-26 |
| | Penn State Nittany Lions | | Sep 4 - W vs. Youngstown St, 44-14 | | Sep 11 - L at Alabama, 3-24 | | Sep 18 - W vs. Kent State, 24-0 | | Sep 25 - W vs. Temple, 22-13 | | Oct 2 - L at Iowa, 3-24 | | Oct 9 - L vs. Illinois, 13-33 | | Oct 16 - Open | | Oct 23 - W at Minnesota, 33-21 | | Oct 30 - W vs. Michigan, 41-31 | | Nov 6 - W vs. Northwestern, 35-21 | | Nov 13 - L at Ohio State, 14-38 | | Nov 20 - W at Indiana, 41-24 | | Nov 27 - L vs. Michigan State, 22-28 | | Dec 4 - Open | | Dec 11 - Open | | Jan 1 - L vs. Florida, 24-37 |
| | Purdue Boilermakers | | Sep 4 - L at Notre Dame, 12-23 | | Sep 11 - W vs. Western Ill, 31-21 | | Sep 18 - W vs. Ball State, 24-13 | | Sep 25 - L vs. Toledo, 20-31 | | Oct 2 - Open | | Oct 9 - W at Northwestern, 20-17 | | Oct 16 - W vs. Minnesota, 28-17 | | Oct 23 - L at Ohio State, 0-49 | | Oct 30 - L at Illinois, 10-44 | | Nov 6 - L vs. Wisconsin, 13-34 | | Nov 13 - L vs. Michigan, 16-27 | | Nov 20 - L at Michigan State, 31-35 | | Nov 27 - L vs. Indiana, 31-34 OT |
| | Wisconsin Badgers | | Sep 4 - W at UNLV, 41-21 | | Sep 11 - W vs. San Jose St, 27-14 | | Sep 18 - W vs. Arizona State, 20-19 | | Sep 25 - W vs. Austin Peay, 70-3 | | Oct 2 - L at Michigan State, 24-34 | | Oct 9 - W vs. Minnesota, 41-23 | | Oct 16 - W vs. Ohio State, 31-18 | | Oct 23 - W at Iowa, 31-30 | | Oct 30 - Open | | Nov 6 - W at Purdue, 34-13 | | Nov 13 - W vs. Indiana, 83-20 | | Nov 20 - W at Michigan, 48-28 | | Nov 27 - W vs. Northwestern, 70-23 | | Dec 4 - Open | | Dec 11 - Open | | Jan 1 - L at TCU, 19-21 |
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